Have We Found the True Cause of Alzheimer's?

Alzheimer’s has been a mysterious disease ever since it was discovered. Considered to be a condition that fits into the dementia category, Alzheimer’s disease is characterized by physical changes in the brain that deteriorate brain function, cognitive ability, and memory in a certain pattern. People who are at least 65 years old are most often affected, however, there are also early-onset cases.

The progression of Alzheimer’s happens over decades and since the brain is such a complicated organ, it has been difficult for scientists to study.

The brain of the patient that had the first named case of Alzheimer’s disease was found to have amyloid (protein) plaques and tao tangles (tangles of fibers) within it. These abnormalities have long been considered by medical professionals to be one of the main causes of the disease, however recent studies suggest that the true cause could be another condition that happens initially, and this abnormal tissue growth may be a secondary symptom.

Stock Images and Stock Video of Alzheimer’s Disease

Scientists came out with new research this year that highlights chronic inflammation as one of the possible causes, based on the body’s tendency to kill off cells or change the genetic code within cells when inflamed for a long period of time. Alzheimer’s is considered a genetic disorder, meaning that it is caused by mutated genes. This also means that the disease can be inherited from a family member. Because the gene mutation that chronic inflammation causes can get worse as the body ages, it makes a good parallel to the fact that Alzheimer’s usually sets in at an older age.

Although inflammation seems to be a viable candidate, many studies still need to be conducted to see if anti-inflammatory drugs ease the progression or onset of Alzheimer's and dementia.

Currently, there are studies being conducted to find out if we would be able to use an existing anti-inflammatory drug as a treatment or preventative measure. If one is found to work, it would be more accessible to obtain as well as cheaper for both the patient and developers.

At this point in time Alzheimer’s is incurable and lifelong, however, if we are able to pinpoint the cause of this condition we will be able to prevent the onset of the disease and will be well on our way to finding a cure.

• medicalxpress.com/news/2018-09-scientists-reveal-ground-breaking-alzheimer-disease
• alz.org
• nia.nih.gov/health/alzheimers-disease-fact-sheet
• sciencedaily.com/releases/2018/05/180502104103.htm
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Explore the Human Microbiome

The idea of bacteria creeping through your body might be less than appetizing. We often associate the presence of bacteria in our bodies (especially in our digestive system) with infections, viruses, and food poisonings. However, scientific findings have uncovered the fact that there are also many types of good bacteria that are essential to our health. This collection of good and bad bacteria within our bodies have also been discovered to be strikingly diverse from person to person.

The definition of the human microbiome is still somewhat ambiguous and disputed but is commonly known to be the vast ecosystem of microscopic organisms (microbes) living within us. According to the National Center for Biotechnology Information (NCBI), we consist of 10-100 trillion microbiota, also known as microbial cells. These cells hold genes that determine cell behavior.

Stock Images and Stock Video of Microbes

Scientists have become specifically interested in the gut (our stomach and intestines) as a location that holds a notably vast collection of microbes. Believe it or not, the large intestine houses good bacteria, such as probiotics, that fight the bad bacteria and keeps us healthy. The ratio of good bacteria to bad can change and partly depends on your immune system or diet choices. If good bacteria becomes low in numbers, risk of infection and virus development increases.

One of the fascinating aspects of our microbiomes is that everyone's is distinctly unique. We, as humans, have a much different microbiome than other animals, but ours also differ from person to person. Even the collection of organisms in your mouth is different than the community of organisms in your gut.

Because each person's microbiome is so individualized, researchers are recognizing that this information could be valuable for practical usage in medicine. A patient's microbiome could be used similarly to a fingerprint, but instead of merely identifying the patient, medical professionals could gain a better understanding about what is going on within the patient's body and be able to make more educated predictions about procedures and treatments needed.

Microbial Mugs, Notebooks, and Other Custom Gifts

As more and more scientific findings of this topic surface, it becomes increasingly more exciting to find out how this knowledge will help us solve many unanswered questions that have to do with anatomical behavior, virus prevention, and even evolution. Our microbiomes seem to be the mysterious key that could open many doors to the understanding of the human body.

• learn.genetics.utah.edu/content/microbiome
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426293
• http://www.nutritionnews.abbott/nutrition-as-medicine/the-role-of-the-microbiome-in-gut-health-
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They'll Hijack Your Body to Replicate Themselves

Zombies? Science Fiction? Fantasy? No, it’s the very real flu virus, cold virus, rabies, HIV, ebola or any other viruses.

Viruses are microscopic nonliving organisms that can only reproduce by hijacking the production mechanism inside a living host’s cells. The virus replicates itself until the cell bursts, spreading the virus further. This usually means death to each cell that becomes infected. If the host’s immune system cannot destroy the virus, ultimately it can mean a very bad outcome for the host as well.

They differ from bacteria in that bacteria are alive, reproduce through fission (splitting apart) and carry on metabolic functions such as digestion.

Stock Images of Bacteria and Viruses

Viruses cannot reproduce on their own. They need to attach themselves to a host’s cells and inject it with their DNA/RNA, taking over the cell’s “machinery” to manufacture and reproduce. This continues until the cell literally bursts. The new viruses go on the hunt for more cells to continue this cycle.

Viruses are 10 to 100 times smaller than bacteria. Common water filters can block bacteria, however viruses can pass through many common filters.

Many bacteria are beneficial and even necessary for human existence. Our digestive tracts are filled with good bacteria - Normal Flora - that help break down food and even produce vitamins, such as vitamin K, that are critical to our well-being.

We all know there are also harmful bacteria such as Streptococcus pyogenes that causes strep throat or E. coli that causes food poisoning.

But there are no beneficial viruses that we know of. In fact, a type of virus called a bacteriophage even infects and kills bacteria.

Viral & Bacterial T-shirts, Bags and More…

Antibiotics are useless against viruses. Antibiotics only kill off bacteria, which is why doctors will only prescribe them once they are certain an illness is caused by a bacteria and not a virus.

Even though antiviral drugs do exist, they aren’t even able to kill viruses. They only limit a virus’s ability to develop further.

The best methods for keeping safe from these dangerous invaders in the first place is to practice basic hygiene and common sense. Washing your hands frequently, getting the flu shot, staying clear of wild animals that may carry rabies such as raccoons and avoiding contact with anyone already infected especially if they coughing or sneezing, are some of the leading precautions you can take.

• webmd.com
• wikipedia.com
• sciencedaily.com

The Fascinating Journey of Blood Through Your Body

Did you know that your body houses millions of vessels that are circulating blood at this very moment? In fact, if all the blood vessels in the average adult were connected in one line from beginning to end, they would stretch 100,000 miles. The circulatory (or cardiovascular) system carries blood all throughout your body to transport nutrients, allow for essential body functions like breathing, and maintain an overall homeostasis.

Arteries, veins, and capillaries are the three different types of blood vessels that make blood circulation possible. Veins transport deoxygenated or waste-rich blood that will eventually be filtered, and arteries carry the filtered, oxygenated blood. Capillaries are the middleman of blood circulation, as they enable the exchange of blood between arteries and veins.

Stock Video of Blood Flow and Circulatory Anatomy

Blood Drop on Finger

There are two types of blood circulation: pulmonary and systemic. Pulmonary circulation is the transportation of blood to the lungs so that the blood becomes oxygenated and can return to the heart. This oxygenated blood is then used within systemic circulation.

During systemic circulation, the heart pumps oxygenated blood out to the rest of the body through the arteries. Capillaries deoxygenate the blood by swapping out the oxygen with carbon dioxide, and they then deliver the deoxygenated blood to the veins. The veins carry the deoxygenated blood back to the heart to start the pulmonary cycle over again.

This intricate and elegant system is happening constantly within your body. Without it, you would have no digestive system or immune system, and even your hormones wouldn't be able to be expressed.

Staying healthy, hydrating, and exercising regularly can help ensure that you're taking care of your circulatory system and everything is flowing smoothly.

Circulatory System Mugs, Notebooks, and Other Custom Gifts

• fi.edu
• ncbi.nlm.nih.gov
• innerbody.com

The Heartbreak of Psoriatic Arthritis, Seriously

"The Heartbreak of Psoriasis" has long been a punchline in the media, used in a quirky 1960's TV commercial, an avant-garde play, and even a hit song.

But, having psoriasis, and especially psoriatic arthritis is serious. Psoriasis is a non-contagious condition related to immune system function and often runs in families. There is no cure, and the itching, cracked, bleeding skin and embarrassing silvery thick scales brings anguish to those who are afflicted. It can range from the occasional small patch with years of remission to a lifelong full-body debilitating condition.

View Medical Images of Psoriatic Arthritis

Patients with psoriasis are more likely to have other health issues as well. These include an increased prevalence and risk of inflammatory bowel diseases (IBD), Crohn’s disease and ulcerative colitis. Also, a common ophthalmic disease in these patients is uveitis.

Ointments and creams are a helpful treatment for those with mild to moderate psoriasis, but, there has been little help for patients with 10% - 100% of their skin affected. Now a handful of immunosuppressant and biologic drugs offer miraculous relief.

Unfortunately, these effective drugs do come with side effects including an increased risk of cancer, tuberculosis, kidney problems and susceptibility to life-threatening infections.

Some patients prefer exploring alternative treatments. These range from doctor-approved treatments such as phototherapy with UV lights, pine tar derived formulas and weight loss, to more questionable 'cures' such as swimming in the Dead Sea, smearing yourself with vegetable shortening or megadosing on zinc tablets. A popular ancient treatment was a concoction of onions, sea salt, and urine.
Avoiding triggers such as stress, citrus, red wine, processed meats, gluten, dairy, and others may help some. These do not work for everyone and require self-experimentation over months or years to see results.

No matter how mild or severe your psoriasis, there is a large psychological toll. Cyndi Lauper, Kim Kardashian, Art Garfunkel, LeAnn Rimes and other celebrities who speak openly about their battle with psoriasis bring a positive life outlook to sufferers.

Along with continuing medical research, the future holds promise for those with psoriasis and psoriatic arthritis.

National Psoriasis Foundation

A small percentage of psoriasis patients develop psoriatic arthritis, which painfully swells the joints, deteriorates bones and eventually deforms hands, feet, and the spine to crippling degrees. This spinal condition is called ankylosing spondylitis.

• psoriasis,org
• psoriasis severity, psoriasis.com
• Mayo Clinic Staff, Psoriasis diagnosis and treatment, mayoclinic.org
• Psoriasis Hall of Shame, pinch.com